What Role Does Testosterone Play In Prostate Cancer?
The Role Testosterone Plays in Prostate Cancer: Understanding the Connection
Testosterone is a hormone present in both sexes, although in much higher volume in males. Testosterone has a significant role in the development of the physical characteristics we associate with men—like facial hair, muscle mass, voice tone, and bone density. Some studies suggest high testosterone levels can correlate to a higher prostate cancer risk.
Prostate cancer is the most common cancer among men over 50. It typically develops in the prostate gland, a walnut-sized gland below the bladder.
the percentage of men who will be diagnosed with prostate cancer and those who will require treatment for their malignancy will rise in the coming years. Prostate Cancer in Elderly Men
Testosterone Does Not Cause Prostate Cancer
Although testosterone does not cause prostate cancer, it can stimulate the growth of cancer cells in the prostate gland. This is why prostate cancer treatment often involves reducing the level of testosterone in the body through medication or surgery.
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Androgen deprivation therapy blocks the production of testosterone or the hormone from reaching the prostate gland. This type of therapy can help slow the growth of prostate cancer cells. Still, it can also cause side effects such as decreased libido, erectile dysfunction, and hot flashes. Therefore, the decision to use these drugs should be carefully considered on a case-by-case basis.
It is important to note that not all men with high testosterone levels will develop prostate cancer, and not all men with prostate cancer have high testosterone levels. However, maintaining a healthy testosterone level through regular exercise, a balanced diet, and regular check-ups with a healthcare provider can help reduce the risk of developing prostate cancer.
Testosterone Plays a Complex Role in Prostate Cancer
Overall, the suggestion is that testosterone plays a complex role in the development and progression of prostate cancer, and the regulation of testosterone levels may be a potential target for the prevention and treatment of this disease.
References for Role of Testosterone in Prostate Cancer
“Journal of Clinical Oncology:Hormonal Predictors of Prostate Cancer: A Meta-Analysis” – https://www.researchgate.net/publication/314023402_Hormonal_Predictors_of_Prostate_Cancer_A_Meta-Analysis
UK:Testosterone and prostate cancer risk: the plot thickens as study reveals intriguing clues” – https://prostatecanceruk.org/about-us/news-and-views/2017/11/testosterone-and-prostate-cancer-risk-the-plot-thickens
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